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Neuroradiologiske forandringer ved undertrykkelse af tics

Forfatter(e)
Sara Bohn Larsen, Camilla Birgitte Sørensen, Liselotte Skov & Nanette Mol Debes Børneafdelingen, Herlev Hospital Ugeskr Læger 2017;179:V06160424
Reference: 
Ugeskr Læger 2017;179:V06160424
Blad nummer: 
Sidetal: 
2-5
Neuroradiological changes by suppression of tics
Tourette’s syndrome is characterized by involuntary tics. First choice of treatment has been pharmacological, but recently, behavioural therapy teaching patients to suppress their tics has been introduced. Neuroimaging studies have shown an increased activity in the prefrontal cortex, temporal lobes and caudate nucleus, and a decreased activity in globus pallidus and putamen during inhibition of tics. The activity in the frontal lobes changes with age, probably caused by a lack of compensatory hypertrophy. In order to fully understand the mechanism behind behavioural therapy further studies are needed.
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