Content area


No effect of specific anti-smoking advice after stroke

Nete Hornnes1, Klaus Larsen2, Tove Brink-Kjær3 & Gudrun Boysen4 FROM: 1 )Department of Neurology, Herlev Hospital, 2) Department of Biostatistics, Lundbeck A/S, 3) Department of Clinical Biochemistry, Gentofte Hospital, 4) Department of Neurology, Bispebjerg Hospital


Many stroke survivors would benefit from modification of their lifestyle in order to reduce their risk of recurrent stroke. We investigated if tailored smoking cessation advice would yield a higher smoking cessation rate and a higher rate with sustained abstinence in ex-smokers in the intervention group than among controls.


Patients admitted with an acute stroke or a transient ischaemic attack were included in a randomised controlled trial focusing on control of lifestyle risk factors and hypertension. Here, we report the intervention focused on smoking cessation. We used multiple logistic regression analysis to identify patient characteristics associated with smoking cessation. Analyses were by intention to treat excluding those who died or suffered severe disease.


We included 254 patients with a history of smoking. Two years after inclusion, 15 of 57 (26%) baseline smokers in the intervention group had stopped smoking versus eight of 56 (14%) among controls (p = 0.112). Living with a partner (p = 0.012), having at least ten years of education (p = 0.012), and not being exposed to smoking at home (p = 0.036) were independent predictors of smoking cessation.


We did not achieve our aim of higher smoking cessation rates in the intervention group. Future smoking cessation interventions should be more intensive, focus on patients’ social circumstances and, if possible, involve patients’ relatives.


This study was supported by the Ludvig and Sara Elsass Foundation, the Lundbeck Foundation and The Danish Heart Foundation (Grant 07-4-B703-A1378-22384F).


This protocol is registered with Clinical (NCT 00253097).

CORRESPONDENCE: Nete Hornnes. E-mail:

CONFLICTS OF INTEREST: Disclosure forms provided by the authors are available with the full text of this article at

REFERENCE: Dan Med J 2014;61(4):A4816

Blad nummer: 

Right side

af Sarah Wåhlin-Jacobsen | 12/08
2 kommentarer
af Sebastian von Huth | 09/08
2 kommentarer
af Philippe Adam Grandjean | 08/08
5 kommentarer
af Rune Jacobsen | 06/08
5 kommentarer
af Anna Sofie Bech | 02/08
4 kommentarer
af Lars Bønløkke | 01/08
13 kommentarer
af Henrik Ib Nielsen | 01/08
2 kommentarer
af Jamila Stephanie Hussein Eriksen | 01/08
2 kommentarer