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Opdatering af neonatal ukonjugeret hyperbilirubinæmi i Danmark

Forfatter(e)

Mette Line Donneborg1,2, Bo Mølholm Hansen3, Jesper Padkær Petersen4, Pernille Kure Vandborg5 & Finn Ebbesen6

1) Børn og Unge, Regionshospital Nordjylland, Hjørring

2) Klinisk Institut, Det Sundhedsvidenskabelige Fakultet, Aalborg Universitet

3) Børne- og Ungeafdelingen, Nordsjællands Hospital, Hillerød

4) Børn og Unge, Aarhus Universitetshospital

5) Børn og Unge, Regionshospitalet Viborg

6) Børne- og Ungeafdelingen, Aalborg Universitetshospital

Ugeskr Læger 2020;182:V11190671

Reference: 
UgeskrLæger 2020;182:V11190671
Blad nummer: 
An update on unconjugated neonatal hyperbilirubinaemia in Denmark

Mette Line Donneborg, Bo Mølholm Hansen, Jesper Padkær Petersen,
Pernille Kure Vandborg & Finn Ebbesen:

Ugeskr Læger 2020;182:V11190671

Approximately 60% of term newborn infants are jaundiced during the first week of life, which is caused by unconjugated bilirubin. Bilirubin encephalopathy is seen with severe hyperbilirubinaemia, when unbound bilirubin crosses the blood-brain barrier. The chronic form is called kernicterus spectrum disorder. To avoid this devastating condition, the treatment of choice for neonatal hyperbilirubinaemia is phototherapy, which is most efficient with LED light of 478-nm wavelength. In this review, we argue, that a systematic approach to hyperbilirubinaemic infants as well as surveillance of extreme neonatal hyperbilirubinaemia is highly important.

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