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Perioperativ heparin-bridging er sjældent indiceret

Forfatter(e)
Jørn Dalsgaard Nielsen1, Anna-Marie Bloch Münster2 & Steen Elkjær Husted3 1) Hjerteambulatoriet, Frederiksberg Hospital 2) Klinisk Biokemisk Afdeling, Hospitalsenheden Vest, Regionshospitalet Herning 3) Medicinsk Afdeling B, Hospitalsenheden Vest, Regionshospitalet Herning Ugeskr Læger 2016;178:V12150952
Reference: 
Ugeskr Læger 2016;178:V12150952
Blad nummer: 
Sidetal: 
2-5
Perioperative heparin bridging is rarely indicated
Meta-analyses of cohort studies and a recent randomized, placebo-controlled study have shown that perioperative bridging of warfarin therapy with therapeutic doses of heparin results in a multi-fold increase in major bleeding but no reduction in the incidence of thromboembolism. It is time to reconsider heparin bridging: When is heparin bridging superfluous? When is prophylactic dosage indicated? And when is it safe to use therapeutic dosing?
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