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Peroperativ methadon til behandling af postoperative smerter

Forfatter(e)

Camilla Gaarsdal Uhrbrand1, Kristian D. Friesgaard1, Lone D. Brix2, Jytte F. Møller1 & Lone Nikolajsen1

1) Bedøvelse og Operation, Aarhus Universitetshospital 2) Bedøvelse, Operation og Intensiv, Regionshospitalet Horsens

Ugeskr Læger 2020;182:V02200092

Reference: 
UgeskrLæger 2020;182:V02200092
Blad nummer: 
Intraoperative methadone for post-operative pain

Camilla Gaarsdal Uhrbrand, Kristian D. Friesgaard, Lone D. Brix, Jytte F. Møller & Lone Nikolajsen

Ugeskr Læger 2020;182:V02200092

Methadone is an opioid with several desirable pharmacological features, including a long elimination half-life. Several studies have suggested that a single intraoperative dose reduces post-operative pain and opioid consumption. In this review, we summarise the current knowledge of intraoperative methadone for the treatment of post-operative pain and propose recommendations for clinical use and future research.

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