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Personlig medicin nødvendiggør paradigmeskifte i evidensbegrebet

Forfatter(e)
Ingolf Nielsen, Bjarne Sigurd & Bjarne Ørskov

Ugeskr Læger 2019;181:V07180480
Reference: 
Ugeskr Læger 2019;181:V07180480
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Ingolf Nielsen, Bjarne Sigurd & Bjarne Ørskov:

Personalised medicine requires a paradigm shift in the concept of evidence

Ugeskr Læger 2019;181:V07180480

Personalised medicine via a central biobank will require the introduction of a paradigm shift navigating by detecting pattern and correlation, instead of evidence of limited use in our complex environment. Accordingly, to make sense, population-wide data comprising “deep phenotype” including genetics, must be submitted to evaluation by “machine intelligence”, based on ”unsupervised learning”


– the algorithm concomitantly improving its power with increasing mass of data. A system not based on deductive logic cannot be checked by logic but must be taken on face value.

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