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Screening for cerebrale arteriovenøsemalformationer ved mb. Osler

Forfatter(e)

Simon Kjær Simonsen1, Troels Halfeld Nielsen2, Rikke Beese Dalby3, Annette Dam Fialla4, Bibi Lange5, Pernille Mathiesen Tørring6, Anabel Diaz7 & Anette Drøhse Kjeldsen5

1) Diabetes og Hormonsygdomme, Aarhus Universitetshospital, 2) Neurokirurgisk Afdeling, Odense Universitetshospital, 3) Røntgen og Skanning, Aarhus Universitetshospital, 4) Medicinsk Gastroenterologisk Afdeling, Odense Universitetshospital, 5) Øre-, Næse og Halskirurgisk Afdeling, Odense Universitetshospital, 6) Klinisk Genetisk Afdeling, Odense Universitetshospital, 7) Radiologisk Afdeling, Odense Universitetshospital

Ugeskr Læger 2021;183:V12200905

Reference: 
Ugeskr Læger 2021;183:V12200905
Screening for cerebral arteriovenous malformations in patients with hereditary haemorrhagic telangiectasia

Simon Kjær Simonsen, Troels Halfeld Nielsen, Rikke Beese Dalby, Annette Dam Fialla, Bibi Lange, Pernille Mathiesen Tørring, Anabel Diaz & Anette Drøhse Kjeldsen

Ugeskr Læger 2021;183:V12200905

Patients with hereditary haemorrhagic telangiectasia (HHT) are known to suffer from cerebral arteriovenous malformations (CAVMs). In this review, we explore existing literature for bleeding risk, interventional therapy and neuroradiological features in HHT-related CAVMs. Studies estimate the annual intracerebral haemorrhage rate of CAVMs in HHT patients to be 0.667-1.014%. The clinician must balance bleeding risk and the non-negligible procedural risks of interventional therapy. We recommend, in agreement with European guidelines, that screening of asymptomatic HHT patients should only be carried out after careful information.

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