Sumatriptan plus naproxen i behandlingen af akutte migræneanfald – en gennemgang af et Cochranereview
Ugeskr Læger 2014;176:V03140155
Sumatriptan plus naproxen for acute migraine attacks in adults
It is of great importance to improve acute treatment of migraine attacks. Non-steroidal anti-inflammatory drugs (NSAID) and triptans have different anti-nociceptive effects, so a combination of these could theoretically lead to more effective acute migraine treatment. A recent meta-analysis investigated the combined effect of sumatriptan and naproxen and found it to be more effective than sumatriptan alone. However, the number needed to treat was high. Combined sumatriptan/naproxen should be reserved to those without efficient response to triptans.