Ugeskr Læger 2018;180:V01170056
Work-up and treatment of anal cancer
The incidence of anal cancer is increasing. The primary treatment consists of radiotherapy concomitant with chemotherapy. Short- and long-term side effects are common, and supportive care during treatment and rehabilitation after treatment is necessary. Locoregional recurrence is treated with an abdominoperineal resection with sigmoideostomia and/or lymph node exairesis. Staging and treatment is done centralized. The prognosis has improved over the latest 10-20 years with a long-term overall survival of > 70% after primary therapy and approximately 50% after surgical treatment for recurrence.